Article
Failure to replicate the association between NRG1 and schizophrenia using Japanese large sample.
Schizophrenia research - 1 Apr 2008
Ikeda Masashi, Takahashi Nagahide, Saito Shinichi, Aleksic Branko, Watanabe Yuichiro, Nunokawa Ayako, Yamanouchi Yoshio, Kitajima Tsuyoshi, Kinoshita Yoko, Kishi Taro, Kawashima Kunihiro, Hashimoto Ryota, Ujike Hiroshi, Inada Toshiya, Someya Toshiyuki, Takeda Masatoshi, Ozaki Norio, Iwata Nakao
Abstract excerpt
Systematic linkage disequilibrium (LD) mapping of 8p12-21 in the Icelandic population identified neuregulin 1 (NRG1) as a prime candidate gene for schizophrenia. However, results of replication studies have been inconsistent, and no large sample analyses have been reported. Therefore, we designed this study with the aim of assessing this putative association between schizophrenia and NRG1 (especially HAP(ICE)...
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