Article
Association and interaction analyses of NRG1 and ERBB4 genes with schizophrenia in a Japanese population.
Journal of human genetics - 1 Jan 2008
Shiota Sae, Tochigi Mamoru, Shimada Hiroko, Ohashi Jun, Kasai Kiyoto, Kato Nobumasa, Tokunaga Katsushi, Sasaki Tsukasa
Abstract excerpt
Neuregulin 1 (NRG1) is one of the most promising candidate genes for schizophrenia. A number of replication studies have been conducted, although the results were inconsistent and no susceptible variant has yet been identified. The inconsistency might be attributed to the ethnic difference in allele and haplotype frequencies. However, it is equally possible that one or more genes interacting with NRG1 may also be...
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