Article
Effects of nitric oxide on red blood cell development and phenotype.
Current topics in developmental biology - 1 Jan 2008
Cokić Vladan P, Schechter Alan N
Abstract excerpt
Nitric oxide (NO) is a diffusible free radical generated primarily by NO synthases (NOS), isoenzymes that convert the l-arginine and molecular oxygen to citrulline and NO in cells. Endothelial cells as well as macrophages, components of hematopoietic microenvironment and potent NO producers, play an active role in the modulation of human hematopoietic cell growth and differentiation. A role of NO in erythroid...
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