Article
Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2006
Livasy Chad A, Karaca Gamze, Nanda Rita, Tretiakova Maria S, Olopade Olufunmilayo I, Moore Dominic T, Perou Charles M
Abstract excerpt
Microarray profiling of invasive breast carcinomas has identified five distinct subtypes of tumors (luminal A, luminal B, normal breast-like, HER2 overexpressing, and basal-like) that are associated with different clinical outcomes. The basal-like subtype is associated with poor clinical outcomes and is the subtype observed in BRCA1-related breast cancers. The aim of this study was to characterize the histologic...
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