Article
Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2006
Livasy Chad A, Karaca Gamze, Nanda Rita, Tretiakova Maria S, Olopade Olufunmilayo I, Moore Dominic T, Perou Charles M
Abstract excerpt
Microarray profiling of invasive breast carcinomas has identified five distinct subtypes of tumors (luminal A, luminal B, normal breast-like, HER2 overexpressing, and basal-like) that are associated with different clinical outcomes. The basal-like subtype is associated with poor clinical outcomes...
Topics
- Actins
- Breast
- Breast Neoplasms
- DNA-Binding Proteins
- ErbB Receptors
- Female
- Gene Expression Profiling
- Genes, Tumor Suppressor
- Humans
- Immunohistochemistry
- Keratin-5
