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Article

Antifungal activity of chalcones: a mechanistic study using various yeast strains.

European journal of medicinal chemistry - 1 Oct 2008

Lahtchev K L, Batovska D I, Parushev St P, Ubiyvovk V M, Sibirny A A

Abstract excerpt

We reported the synthesis, antifungal evaluation and study on substituent effects of 21 chalcones. A lot of genetically defined strains belonging to different yeast genera and species, namely Saccharomyces cerevisiae, Hansenula polymorpha and Kluyveromyces lactis, were used as test organisms. Concerning the mode of the antifungal action of chalcones it was shown that DNA was probably not the main target for the...

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Identifiers

PMID: 18280009
DOI: 10.1016/j.ejmech.2007.12.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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