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Article

Molecular mechanisms of action of herbal antifungal alkaloid berberine, in Candida albicans.

PloS one - 1 Jan 2014

Dhamgaye Sanjiveeni, Devaux Frédéric, Vandeputte Patrick, Khandelwal Nitesh Kumar, Sanglard Dominique, Mukhopadhyay Gauranga, Prasad Rajendra

Abstract excerpt

Candida albicans causes superficial to systemic infections in immuno-compromised individuals. The concomitant use of fungistatic drugs and the lack of cidal drugs frequently result in strains that could withstand commonly used antifungals, and display multidrug resistance (MDR). In search of novel fungicidals, in this study, we have explored a plant alkaloid berberine (BER) for its antifungal potential. For this,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25105295
DOI: 10.1371/journal.pone.0104554
PMCID: PMC4126717

Genes

HSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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