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Article

Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling.

Virology - 10 May 2008

Johnson Karen E, Song Byeongwoon, Knipe David M

Abstract excerpt

Host cells respond to viral infection by many mechanisms, including the production of type I interferons which act in a paracrine and autocrine manner to induce the expression of antiviral interferon-stimulated genes (ISGs). Viruses have evolved means to inhibit interferon signaling to avoid induction of the innate immune response. Herpes simplex virus 1 (HSV-1) has several mechanisms to inhibit type I interferon...

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Identifiers

PMID: 18279905
DOI: 10.1016/j.virol.2008.01.001
PMCID: PMC2638114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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