Article
Serum chemokine levels in Hodgkin lymphoma patients: highly increased levels of CCL17 and CCL22.
British journal of haematology - 1 Mar 2008
Niens Marijke, Visser Lydia, Nolte Ilja M, van der Steege Gerrit, Diepstra Arjan, Cordano Pablo, Jarrett Ruth F, Te Meerman Gerard J, Poppema Sibrand, van den Berg Anke
Abstract excerpt
Hodgkin lymphoma (HL) is characterized by a minority of neoplastic Hodgkin-Reed Sternberg (HRS) cells surrounded by a non-neoplastic reactive infiltrate. As immunological mechanisms appear to be crucial in classical HL pathogenesis, altered serum chemokine levels might be related to disease activity. Serum levels of nine chemokines were examined in 163 untreated HL patients and 334 controls. We investigated...
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