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Article

Mutational analysis of a principal neutralization domain of visna/maedi virus envelope glycoprotein.

The Journal of general virology - 1 Mar 2008

Haflidadóttir Benedikta S, Matthíasdóttir Sigrídur, Agnarsdóttir Gudrún, Torsteinsdóttir Sigurbjorg, Pétursson Gudmundur, Andrésson Ólafur S, Andrésdóttir Valgerdur

Abstract excerpt

We have shown previously that a type-specific neutralization domain is located within a 39 aa sequence in the fourth variable domain of gp135 in visna/maedi virus. We now show that neutralizing antibodies detected early in infection are directed to this epitope, suggesting an immunodominant nature of this domain. Ten antigenic variants were previously analysed for mutations in this region, and all but one were...

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Identifiers

PMID: 18272763
DOI: 10.1099/vir.0.83410-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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