Article
PPARgamma2 Pro12Ala polymorphism in relation to free fatty acids concentration and composition in lean healthy Czech individuals with and without family history of diabetes type 2.
Physiological research - 1 Jan 2008
Bendlová B, Vejražková D, Včelák J, Lukášová P, Burkoňová D, Kunešová M, Vrbíková J, Dvoráková K, Vondra K, Vanková M
Abstract excerpt
Free fatty acids (FFAs) are natural ligands of the PPARgamma2 receptor. FFA plasma concentration and composition may represent one of the factors accounting for high heterogeneity of conclusions concerning the effect of the Pro12Ala on BMI, insulin sensitivity or diabetes type 2 (DM2) susceptibil...
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