Article
Alternative mRNA editing in trypanosomes is extensive and may contribute to mitochondrial protein diversity.
PloS one - 13 Feb 2008
Ochsenreiter Torsten, Cipriano Michael, Hajduk Stephen L
Abstract excerpt
The editing of trypanosome mitochondrial mRNAs produces transcripts necessary for mitochondrial functions including electron transport and oxidative phosphorylation. Precursor-mRNAs are often extensively edited by specific uridine insertion or deletion that is directed by small guide RNAs (gRNAs). Recently, it has been shown that cytochrome c oxidase subunit III (COXIII) mRNAs can be alternatively edited to...
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