Article
Associations of FcepsilonRIbeta E237G polymorphism with wheezing in Taiwanese schoolchildren.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Mar 2008
Lee Y-L, Gilliland F D, Wang J-Y, Lee Y-C, Guo Y L
Abstract excerpt
BACKGROUND: The beta-chain of a high-affinity IgE receptor (FcepsilonRIbeta) has been proposed as a candidate gene for atopic diseases, but previous studies have come to inconsistent conclusions. Because some air pollutants would produce oxidative stress, increase serum IgE, and trigger T-helper type 2 (Th2)-type airway inflammation, the associations of FcepsilonRIbeta polymorphism with wheezing illness may vary...
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