Article
The association between tumor necrosis factor, HLA-DR alleles, and IgE-mediated asthma in Taiwanese adolescents.
Allergy - 1 Sept 2002
Lin Ying-Chu, Lu Cheng-Chan, Su Huey-Jen, Shen Chen-Yang, Lei Huan-Yao, Guo Yueliang Leon
Abstract excerpt
BACKGROUND: Human leukocyte antigen (HLA) DR genes and the tumor necrosis factor (TNF) gene locus are associated with asthma and IgE production. TNFalpha-308G/A frequencies between Japanese and Caucasians in the UK have been found to be different. The roles of HLA-DRB1 and TNF genotypes are unknown in Taiwanese adolescents with IgE-mediated asthma (I-asthma). METHODS: From the population of a 1996 nation-wide...
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