Article
The mitochondrial F1ATPase alpha-subunit is necessary for efficient import of mitochondrial precursors.
The Journal of biological chemistry - 25 Jul 1992
Yuan H, Douglas M G
Abstract excerpt
The mitochondrial import and assembly of the F1ATPase subunits requires, respectively, the participation of the molecular chaperones hsp70SSA1 and hsp70SSC1 and other components operating on opposite sides of the mitochondrial membrane. In previous studies, both the homology and the assembly properties of the F1ATPase alpha-subunit (ATP1p) compared to the groEL homologue, hsp60, have led to the proposal that this...
Topics
- Biological Transport
- Electrophoresis, Gel, Pulsed-Field
- Enzyme Precursors
- Genes, Fungal
- Heat-Shock Proteins
- Intracellular Membranes
- Mitochondria
- Mutation
- Protein Biosynthesis
- Proton-Translocating ATPases
- Saccharomyces cerevisiae
