Association of single nucleotide polymorphisms in glycosylation genes with risk of epithelial ovarian cancer.

doi:10.1158/1055-9965.EPI-07-0565

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Article

Association of single nucleotide polymorphisms in glycosylation genes with risk of epithelial ovarian cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2008

Sellers Thomas A, Huang Yifan, Cunningham Julie, Goode Ellen L, Sutphen Rebecca, Vierkant Robert A, Kelemen Linda E, Fredericksen Zachary S, Liebow Mark, Pankratz V Shane, Hartmann Lynn C, Myer Jeff, Iversen Edwin S, Schildkraut Joellen M, Phelan Catherine

Abstract excerpt

Studies suggest that underglycosylation of the cell membrane mucin MUC1 may be associated with epithelial ovarian cancer. We identified 26 genes involved in glycosylation and examined 93 single nucleotide polymorphisms (SNP) with a minor allele frequency of > or =0.05 in relation to incident ovarian cancer. Cases were ascertained at the Mayo Clinic, Rochester, MN (n = 396) or a 48-county region in North Carolina...

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Identifiers

PMID: 18268124
DOI: 10.1158/1055-9965.EPI-07-0565
PMCID: PMC3303215

Genes

GALNT1
MUC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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