Article
The modulatory influence of polymorphism of the serotonin transporter gene on characteristics of mental maladaptation in relatives of patients with endogenous psychoses.
Neuroscience and behavioral physiology - 1 Mar 2008
Alfimova M V, Golimbet V E, Korovaitseva G I, Lezheiko T V, Abramova L I, Kaleda V G, Barkhatova A N
Abstract excerpt
A number of studies have reported an association between 5-HTTLPR, a polymorphism of the serotonin transporter gene, and the development of depressive states in response to a variety of distal and proximal stressors. We report here studies of the effects of the 5-HTTLPR polymorphism on the probab...
Topics
- Adaptation, Psychological
- Adult
- Family
- Female
- Genetic Predisposition to Disease
- Humans
- Male
- Middle Aged
- Pedigree
- Polymorphism, Genetic
- Psychotic Disorders
- Schizophrenia
- Serotonin Plasma Membrane Transport Proteins
- Sex Factors