Article
[Serotonin transporter gene polymorphism modulates psychic maladaptation in relatives of patients with endogenic psychoses].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2007
Alfimova M V, Golimbet V E, Korovaĭtseva G I, Lezheĭko T V, Abramova L I, Kaleda V G, Barkhatova A N
Abstract excerpt
An association between serotonin transporter gene 5-HTTLPR polymorphism and development of depressive states in response to different distant and proximal stressors has been reported previously. We studied 5-HTTLPR polymorphism effect on probability of development of mental maladaptation and its peculiarities in 224 relatives of patients with severe chronic mental disorders: schizophrenia, schizoaffective and...
Topics
- Adaptation, Psychological
- Adult
- DNA
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Pedigree
- Polymerase Chain Reaction
