Article
Four SNPs on chromosome 9p21 in a South Korean population implicate a genetic locus that confers high cross-race risk for development of coronary artery disease.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2008
Shen Gong-Qing, Li Lin, Rao Shaoqi, Abdullah Kalil G, Ban Ji Min, Lee Bok-Soo, Park Jeong Euy, Wang Qing K
Abstract excerpt
OBJECTIVE: Recent genome-wide association studies have identified 4 SNPs on chromosome 9p21 associated with CAD (rs10757274 and rs2383206) and myocardial infarction (MI: rs2383207 and rs10757278) in White populations in Northern Europe and North America. We aimed to determine whether this locus confers significant susceptibility to CAD in a South Korean population, and thus cross-race susceptibility to CAD....
Read the complete abstract on PubMed