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Article

Ectopic expression of methionine aminopeptidase-2 causes cell transformation and stimulates proliferation.

Oncogene - 26 Jun 2008

Tucker L A, Zhang Q, Sheppard G S, Lou P, Jiang F, McKeegan E, Lesniewski R, Davidsen S K, Bell R L, Wang J

Abstract excerpt

Methionine aminopeptidase-2 (MetAP2) processes N-terminal methionine from nascent cellular proteins. Inhibition of MetAP2 has been shown to block angiogenesis and suppress tumor growth in preclinical tumor models. However, the biological role of MetAP2 in cancer is not well understood. We examine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18264137
DOI: 10.1038/onc.2008.14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18264137-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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