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Methionine aminopeptidase‑2 is a pivotal regulator of vasculogenic mimicry

15 Dec 2021

Abstract excerpt

Vasculogenic mimicry (VM) is the formation of a blood supply system that confers aggressive and metastatic properties to tumors and correlates with a poor prognosis in cancer patients. Thus, the inhibition of VM is considered an effective approach for cancer treatment, although such a mechanism remains poorly described. In the present study, we examined methionine aminopeptidase‑2 (MetAP2), a key factor of...

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PMID: 34913067
DOI: 10.3892/or.2021.8242

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