Article
Effect of gefitinib challenge to initial treatment with non-small cell lung cancer.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Dec 2011
Chen Xiaofeng, Li Wei, Hu Xiaoli, Geng Yiting, Wang Rong, Yin Yongmei, Shu Yongqian
Abstract excerpt
PURPOSES: This study was conducted to assess the efficacy and toxicity of gefitinib as first line treatment in patients with advanced non-small-cell lung cancer (NSCLC). METHODS: Tumor tissue, derived from either the original tumor or the metastatic or recurrent site was taken from chemo-naïve patients with advanced (stage IIIB, IV and recurrent) NSCLC. Tumor genomic DNA underwent direct sequencing for EGFR exons...
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