Article
Association of TNF-α (-238 and -308) promoter polymorphisms with susceptibility of oral squamous cell carcinoma in North Indian population.
Cancer biomarkers : section A of Disease markers - 1 Jan 2015
Singh Prithvi Kumar, Bogra Jaishri, Chandra Girish, Ahmad Mohammad Kaleem, Gupta Rajni, Kumar Vijay, Jain Amita, Ali Mahdi Abbas
Abstract excerpt
BACKGROUND: The pro-inflammatory cytokines play an essential role in immune response and are involved in a variety of inflammatory and infectious disease. Tumor necrosis factor alpha (TNF-α) gene polymorphism has been a potential determinant of susceptibility to various types of cancer. OBJECTIVE: To evaluate the association of TNF-α gene promoter (-238) G/A and (-308) G/A polymorphisms with the susceptibility of...
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