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Article

West Nile virus genome cyclization and RNA replication require two pairs of long-distance RNA interactions.

Virology - 30 Mar 2008

Zhang Bo, Dong Hongping, Stein David A, Iversen Patrick L, Shi Pei-Yong

Abstract excerpt

West Nile virus (WNV) genome cyclization and replication require two pairs of long-distance RNA interactions. Besides the previously reported 5'CS/3'CSI (conserved sequence) interaction, a 5'UAR/3'UAR (upstream AUG region) interaction also contributes to genome cyclization and replication. WNVs containing mutant 5'UARs capable of forming the 5'/3' viral RNA interaction were replicative. In contrast, WNV...

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PMID: 18258275
DOI: 10.1016/j.virol.2008.01.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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