Article
Association of tumor necrosis factor-alpha and interleukin-1 gene polymorphisms with silicosis.
Toxicology and applied pharmacology - 1 Apr 2001
Yucesoy B, Vallyathan V, Landsittel D P, Sharp D S, Weston A, Burleson G R, Simeonova P, McKinstry M, Luster M I
Abstract excerpt
Silicosis, an interstitial lung disease prevalent among miners, sand blasters, and quarry workers, is manifested as a chronic inflammatory response leading to severe pulmonary fibrotic changes. Proinflammatory cytokines, such as TNFalpha and IL-1, produced in the lung by type II epithelial cells...
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