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Article

Genetic alterations of the Cdx2 gene in gastric cancer.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jan 2008

Song Jae Hwi, Kim Chang Jae, Cho Yong Gu, Chae Jiun Suk, Cao Zhang, Nam Suk Woo, Lee Jung Young, Park Won Sang

Abstract excerpt

Gastric atrophy and intestinal metaplasia are generally considered precancerous lesions of the stomach; Cdx2 plays an important role in intestinal metaplasia and gastric carcinogenesis. To elucidate the potential etiological role of the Cdx2 gene in gastric carcinogenesis, we analyzed genetic mutations and allelic loss in the Cdx2 gene of 95 sporadic gastric cancers. We found two somatic missense mutations in the...

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PMID: 18254783
DOI: 10.1111/j.1600-0463.2008.00881.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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