Article
Biogenesis of type I cytopathic vacuoles in Semliki Forest virus-infected BHK cells.
Journal of virology - 1 Mar 1991
Peränen J, Kääriäinen L
Abstract excerpt
We investigated the biogenesis of type I cytopathic vacuoles (CPVIs) in Semliki Forest virus (SFV)-infected cells by immunofluorescence and electron microscopy. By using the ts1 mutant of SFV at the restrictive temperature to avoid superinfection, we showed that the multiplicity of infection affects the time of appearance but not the number of CPVIs in a cell. Formation of CPVIs did not require incoming virus...
Topics
- Animals
- Capsid
- Cell Line
- Cell Transformation, Viral
- Cricetinae
- Fluorescent Antibody Technique
- Kidney
- Microscopy, Electron
- Mutation
- Semliki forest virus
- Temperature
- Vacuoles