Article
Role of matrix protein in cytopathogenesis of vesicular stomatitis virus.
Journal of virology - 1 Apr 1990
Blondel D, Harmison G G, Schubert M
Abstract excerpt
The matrix (M) protein of vesicular stomatitis virus (VSV) plays an important structural role in viral assembly, and it also has a regulatory role in viral transcription. We demonstrate here that the M protein has an additional function. It causes visible cytopathic effects (CPE), as evidenced by the typical rounding of polygonal cells after VSV infection. We have analyzed a temperature-sensitive mutant of the M...
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