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Article

Role of matrix protein in cytopathogenesis of vesicular stomatitis virus.

Journal of virology - 1 Apr 1990

Blondel D, Harmison G G, Schubert M

Abstract excerpt

The matrix (M) protein of vesicular stomatitis virus (VSV) plays an important structural role in viral assembly, and it also has a regulatory role in viral transcription. We demonstrate here that the M protein has an additional function. It causes visible cytopathic effects (CPE), as evidenced by the typical rounding of polygonal cells after VSV infection. We have analyzed a temperature-sensitive mutant of the M...

Topics

Animals
Base Sequence
Cells, Cultured
Cytopathogenic Effect, Viral
Genetic Vectors
Molecular Sequence Data
Mutation
Oligonucleotides
Oligonucleotides, Antisense
RNA, Messenger
RNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Simian virus 40

Transfection

Vesicular stomatitis Indiana virus

Viral Matrix Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 2157054
DOI: 10.1128/JVI.64.4.1716-1725.1990
PMCID: PMC249309

Genes

CPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2157054-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Role of matrix protein in cytopathogenesis of vesicular stomatitis virus.PMID 2157054Read ↗

Identification of two additional translation products from the matrix (M) gene that contribute to vesicular stomatitis virus cytopathology.Semantic proximity Read ↗

Activity of vesicular stomatitis virus M protein mutants in cell rounding is correlated with the ability to inhibit host gene expression and is not correlated with virus assembly function.Semantic proximity Read ↗

The Cell-Rounding Activity of the Vesicular Stomatitis Virus Matrix Protein Is due to the Induction of Cell DeathSemantic proximity Read ↗

Sequential disassembly of the cytoskeleton in BHK21 cells infected with vesicular stomatitis virus.Semantic proximity Read ↗

Matrix Protein and Another Viral Component Contribute to Induction of Apoptosis in Cells Infected with Vesicular Stomatitis VirusSemantic proximity Read ↗

Complementation of M gene mutants of vesicular stomatitis virus by plasmid-derived M protein converts spherical extracellular particles into native bullet shapes.Semantic proximity Read ↗

Respiratory Syncytial Virus Matrix (M) Protein Interacts with Actin In Vitro and in Cell CultureSemantic proximity Read ↗

Interactions of normal and mutant vesicular stomatitis virus matrix proteins with the plasma membrane and nucleocapsids.Semantic proximity Read ↗

Mutations in the glycoprotein of vesicular stomatitis virus affect cytopathogenicity: potential for oncolytic virotherapy.Semantic proximity Read ↗

Ability of the matrix protein of vesicular stomatitis virus to suppress beta interferon gene expression is genetically correlated with the inhibition of host RNA and protein synthesis.Semantic proximity Read ↗

Potency of wild-type and temperature-sensitive vesicular stomatitis virus matrix protein in the inhibition of host-directed gene expression.Semantic proximity Read ↗

Effect of Vesicular Stomatitis Virus Matrix Protein on Transcription Directed by Host RNA Polymerases I, II, and IIISemantic proximity Read ↗

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