Article
Template RNA Length Determines the Size of Replication Complex Spherules for Semliki Forest Virus
13 Jun 2013
Abstract excerpt
The replication complexes of positive-strand RNA viruses are always associated with cellular membranes. The morphology of the replication-associated membranes is altered in different ways in different viral systems, but many viruses induce small membrane invaginations known as spherules as their replication sites. We show here that for Semliki Forest virus (SFV), an alphavirus, the size of the spherules is...