Article
Bronchial response pattern of antigen presenting cells and regulatory T cells in children less than 2 years of age.
Thorax - 1 Aug 2008
Heier I, Malmström K, Pelkonen A S, Malmberg L P, Kajosaari M, Turpeinen M, Lindahl H, Brandtzaeg P, Jahnsen F L, Mäkelä M J
Abstract excerpt
BACKGROUND: In early childhood, the ability to mount protective immune responses in the airways is impaired, with increased risk of allergic sensitisation to inhaled allergens. Antigen presenting cells (APC) and regulatory T cells (Treg) are important modifiers of T cell immunity but little is known about their distribution in bronchial mucosa at this age. Here the subset distribution of APC and the appearance of...
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