Article
The role of the read through variant of acetylcholinesterase in anxiogenic effects of predator stress in mice.
Behavioural brain research - 16 May 2008
Adamec Robert, Head David, Soreq Hermona, Blundell Jacqueline
Abstract excerpt
This study examined the role of the read through variant of acetylcholinesterase (AChE-R) in lasting changes in murine affective behavior produced by a brief predator stress. AChE-R is elevated by stress in limbic cholinergic circuits implicated in anxiogenic effects of predator stress. The expression of AChE-R was blocked with a systemically administered central acting antisense oligonucleotide for AChE-R...
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