Article
Induction and relaxation dynamics of the regulatory network controlling the type III secretion system encoded within Salmonella pathogenicity island 1.
Journal of molecular biology - 14 Mar 2008
Temme Karsten, Salis Howard, Tullman-Ercek Danielle, Levskaya Anselm, Hong Soon-Ho, Voigt Christopher A
Abstract excerpt
Bacterial pathogenesis requires the precise spatial and temporal control of gene expression, the dynamics of which are controlled by regulatory networks. A network encoded within Salmonella Pathogenicity Island 1 controls the expression of a type III protein secretion system involved in the invasion of host cells. The dynamics of this network are measured in single cells using promoter-green fluorescent protein...
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