Article
Early and transient reverse transcription during primary deltaretroviral infection of sheep.
Retrovirology - 1 Feb 2008
Pomier Carole, Alcaraz Maria T Sanchez, Debacq Christophe, Lançon Agnes, Kerkhofs Pierre, Willems Lucas, Wattel Eric, Mortreux Franck
Abstract excerpt
BACKGROUND: Intraindividual genetic variability plays a central role in deltaretrovirus replication and associated leukemogenesis in animals as in humans. To date, the replication of these viruses has only been investigated during the chronic phase of the infection when they mainly spread through the clonal expansion of their host cells, vary through a somatic mutation process without evidence for reverse...
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