Article
“Ménage à Trois”: The Evolutionary Interplay between JSRV, enJSRVs and Domestic Sheep
9 Dec 2014
Abstract excerpt
Sheep betaretroviruses represent a fascinating model to study the complex evolutionary interplay between host and pathogen in natural settings. In infected sheep, the exogenous and pathogenic Jaagsiekte sheep retrovirus (JSRV) coexists with a variety of highly related endogenous JSRVs, referred to as enJSRVs. During evolution, some of them were co-opted by the host as they fulfilled important biological...
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