Article
Analysis of single nucleotide polymorphisms and haplotypes in the neuropeptide Y gene: no evidence for association with alcoholism in a German population sample.
Alcoholism, clinical and experimental research - 1 Mar 2008
Zill Peter, Preuss Ulrich W, Koller Gabrielle, Bondy Brigitta, Soyka Michael
Abstract excerpt
BACKGROUND: Several lines of evidence from animal and electrophysiological studies indicate that the neuropeptide Y (NPY) gene is involved in the pathophysiology of alcohol dependence. Recent studies have provided evidence for an association between a Leu7Pro polymorphism, as well as 2 promoter single nucleotide polymorphisms (SNPs) in the NPY gene (G-602T, T-399C) and alcohol dependence. The aim of the present...
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