Article
Neuropeptide Y polymorphism and alcohol consumption in middle-aged men.
American journal of medical genetics - 17 Jul 2000
Kauhanen J, Karvonen M K, Pesonen U, Koulu M, Tuomainen T P, Uusitupa M I, Salonen J T
Abstract excerpt
Neuropeptide Y (NPY) plays an important role in the hypothalamic regulation of food intake and energy balance. According to recent findings in animals, NPY also seems to be a potent regulator of alcohol consumption. We used the recently identified Leu(7) to Pro(7) polymorphism in the signal peptide part of NPY to investigate whether the NPY system is associated with alcohol consumption in humans. The subjects (N...
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