Article
Involvement of neurofilaments in the radial growth of axons.
Journal of cell science. Supplement - 1 Jan 1991
Cleveland D W, Monteiro M J, Wong P C, Gill S R, Gearhart J D, Hoffman P N
Abstract excerpt
The control of radial growth of axons is of functional importance because caliber is a principal determinant of conduction velocity in myelinated nerve fibers. Neurofilaments, the major cytoskeletal protein in myelinated nerves, appear to be intrinsic determinants of caliber. Evidence supporting this derives first from the linear relationship between neurofilament content and axonal diameter. Further, following...
Topics
- Animals
- Axons
- Cell Division
- Fluorescent Antibody Technique
- Gene Expression
- Intermediate Filaments
- Mice
- Mice, Transgenic
- Mutation
- Neurofilament Proteins
- Restriction Mapping