Article
Overexpression of the human melanoma-associated antigen ME491 partially suppresses in vivo malignant phenotypes of H-ras-transformed NIH3T3 cells in athymic nude mice.
Melanoma research - 1 Jan 2000
Hotta H, Hara I, Miyamoto H, Homma M
Abstract excerpt
H-ras-transformed NIH3T3 cells that overexpressed a human melanoma-associated antigen ME491 (44-3H) were generated by transfection with the cloned ME491 antigen gene followed by a 'panning' selection, and effects of the antigen overexpression on H-ras-mediated malignant phenotypes were studied. Although in vitro growth properties of the 44-3H overexpresser cells, both anchorage-dependent and -independent, were...
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