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Article

Parallel expression of alphaIIbbeta3 and alphavbeta3 integrins in human melanoma cells upregulates bFGF expression and promotes their angiogenic phenotype.

International journal of cancer - 10 Aug 2005

Döme Balázs, Rásó Erzsébet, Dobos Judit, Mészáros Livia, Varga Norbert, Puskás László G, Fehér Liliána Z, Fehér László Z, Lörincz Tamár, Ladányi Andrea, Trikha Mohit, Honn Kenneth V, Tímár József

Abstract excerpt

Previous studies indicated that transfection of the platelet integrin alphaIIbbeta3 into human melanoma cells expressing integrin alphavbeta3 promoted their in vivo (but not in vitro) growth and cell survival. To reveal the underlying pathomechanism, we have analyzed the angiogenic phenotype of alphaIIbbeta3 integrin-transduced human melanoma cells expressing integrin alphavbeta3. Upon heterotopic or orthotopic...

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Identifiers

PMID: 15761867
DOI: 10.1002/ijc.20991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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