Article
8q24 and prostate cancer: association with advanced disease and meta-analysis.
European journal of human genetics : EJHG - 1 Apr 2008
Cheng Iona, Plummer Sarah J, Jorgenson Eric, Liu Xin, Rybicki Benjamin A, Casey Graham, Witte John S
Abstract excerpt
Compelling evidence demonstrates chromosome 8q24 as a prostate cancer susceptibility locus. Multiple variants within three adjacent regions at 8q24 have recently been identified to impact the risk of prostate cancer. Yet, the role of these variants in more advanced disease has not been rigorously assessed. To examine the relationship between 8q24 variants and advanced disease, we tested 10 previously associated...
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