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Article

The interleukin-4 -34TT and -590TT genotype is correlated with increased expression and protein production in aggressive periodontitis.

Molecular immunology - 1 Jan 2010

Gonzales Jose R, Gröger Sabine, Haley Gabriela, Bödeker Rolf-Hasso, Meyle Jörg

Abstract excerpt

Aggressive periodontitis (AgP) is a severe periodontal disease characterized by rapid destruction of the tissues supporting the teeth in otherwise healthy individuals. The frequency of the interleukin-4 homozygous -34TT and -590TT genotype was increased in patients in comparison with controls. This study aimed to test the functional effect of this specific genotype in AgP patients by analyzing gene expression of...

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Source

Identifiers

PMID: 19959237
DOI: 10.1016/j.molimm.2009.10.025

Genes

STAT6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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