Article
The interleukin-4 -34TT and -590TT genotype is correlated with increased expression and protein production in aggressive periodontitis.
Molecular immunology - 1 Jan 2010
Gonzales Jose R, Gröger Sabine, Haley Gabriela, Bödeker Rolf-Hasso, Meyle Jörg
Abstract excerpt
Aggressive periodontitis (AgP) is a severe periodontal disease characterized by rapid destruction of the tissues supporting the teeth in otherwise healthy individuals. The frequency of the interleukin-4 homozygous -34TT and -590TT genotype was increased in patients in comparison with controls. Th...
Topics
- Adult
- Aggressive Periodontitis
- CD4-Positive T-Lymphocytes
- Female
- Gene Expression Regulation
- Genotype
- Humans
- Immunomagnetic Separation
- Interleukin-4
- Lymphocyte Activation
- Male
- Middle Aged
- RNA, Messenger
- STAT6 Transcription Factor
- Young Adult