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Article

Is there an association between IFN-γ +874A/T polymorphism and periodontitis susceptibility?: A meta-analysis.

Medicine - 1 Jun 2017

Shi Quan, Cai Chuan, Xu Juan, Liu Jinglong, Liu Hongchen, Huo Na

Abstract excerpt

BACKGROUND: Interferon-γ (IFN-γ) is a key proinflammatory cytokine which plays a critical role in the pathogenesis and progression of periodontitis. The single nucleotide polymorphism of +874A/T in human IFN-γ gene can influence the secretion of IFN-γ and affect periodontitis susceptibility. However, the findings of published studies are inconsistent. Therefore, the goal of this meta-analysis is to investigate...

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PMID: 28640144
DOI: 10.1097/MD.0000000000007288
PMCID: PMC5484252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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