Article
Single-nucleotide polymorphisms in the IL-4 and IL-13 promoter region in aggressive periodontitis.
Journal of clinical periodontology - 1 Jun 2007
Gonzales J R, Mann M, Stelzig J, Bödeker R H, Meyle J
Abstract excerpt
INTRODUCTION: IL-4 and IL-13 polymorphisms have been shown to influence the susceptibility to systemic diseases. In this study, possible associations between the IL-4 -590 C-->T, IL-4 -34 C-->T, IL-13 -1112 C-->T and IL-13 -1512 A-->C promoter polymorphisms were investigated in subjects with generalized aggressive periodontitis (AgP) compared with healthy individuals. MATERIAL AND METHODS: Fifty-eight patients...
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