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Article

Reduction of estrogen-induced transformation of mouse mammary epithelial cells by N-acetylcysteine.

The Journal of steroid biochemistry and molecular biology - 1 Mar 2008

Venugopal Divya, Zahid Muhammad, Mailander Paula C, Meza Jane L, Rogan Eleanor G, Cavalieri Ercole L, Chakravarti Dhrubajyoti

Abstract excerpt

A growing number of studies indicate that breast cancer initiation is related to abnormal estrogen oxidation to form an excess of estrogen-3,4-quinones, which react with DNA to form depurinating adducts and induce mutations. This mechanism is often called estrogen genotoxicity. 4-Catechol estroge...

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Share to Acetylcysteine
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18226522
DOI: 10.1016/j.jsbmb.2007.12.003
PMCID: PMC2722841

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18226522-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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