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Article

Mercury-induced cognitive impairment in metallothionein-1/2 null mice.

Neurotoxicology and teratology - 1 Jan 2000

Eddins Donnie, Petro Ann, Pollard Ninitia, Freedman Jonathan H, Levin Edward D

Abstract excerpt

Metallothioneins are central for the metabolism and detoxification of transition metals. Exposure to mercury during early neurodevelopment is associated with neurocognitive impairment. Given the importance of metallothioneins in mercury detoxification, metallothioneins may be a protective factor against mercury-induced neurocognitive impairment. Deletion of the murine metallothionein-1 and metallothionein-2 genes...

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Identifiers

PMID: 18226494
DOI: 10.1016/j.ntt.2007.12.005
PMCID: PMC2694566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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