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Article

Single-stranded DNA-binding protein recruits DNA polymerase V to primer termini on RecA-coated DNA.

The Journal of biological chemistry - 28 Mar 2008

Arad Gali, Hendel Ayal, Urbanke Claus, Curth Ute, Livneh Zvi

Abstract excerpt

Translesion DNA synthesis (TLS) by DNA polymerase V (polV) in Escherichia coli involves accessory proteins, including RecA and single-stranded DNA-binding protein (SSB). To elucidate the role of SSB in TLS we used an in vitro exonuclease protection assay and found that SSB increases the accessibility of 3' primer termini located at abasic sites in RecA-coated gapped DNA. The mutant SSB-113 protein, which is...

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Source

Identifiers

PMID: 18223256
DOI: 10.1074/jbc.M710290200

Genes

SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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