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Article

Methylenetetrahydrofolate reductase 677 T allele protects against persistent HBV infection in West Africa.

Journal of hepatology - 1 Apr 2008

Bronowicki Jean-Pierre, Abdelmouttaleb Idrissia, Peyrin-Biroulet Laurent, Venard Véronique, Khiri Hacène, Chabi Nicodème, Amouzou Emile K, Barraud Hélène, Halfon Philippe, Sanni Ambaliou, Bigard Marc-André, Le Faou Alain, Guéant Jean-Louis

Abstract excerpt

BACKGROUND/AIMS: Homocysteine metabolism is linked to DNA methylation, a mechanism potentially involved in the course of hepatitis B virus (HBV) infection. We evaluated the association of determinants of homocysteine metabolism with the outcome of HBV infection. METHODS: Four hundred and fifty-fi...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18222012
DOI: 10.1016/j.jhep.2007.11.017

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18222012-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Methylenetetrahydrofolate reductase 677 T allele protects against persistent HBV infection in West Africa.PMID 18222012Read ↗

Impact of methylene-tetrahydrofolate reductase gene C677T and A1298C polymorphisms as a risk factor for hepatitis B virus infection.Semantic proximity Read ↗

The MTHFR C677T mutation is not a risk factor recognized for HBV-related HCC in a population with a high prevalence of this genetic marker.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphisms in Burkina Faso: impact on plasma fasting homocysteine and after methionine loading test.Semantic proximity Read ↗

High prevalence of hyperhomocysteinemia related to folate deficiency and the 677C-->T mutation of the gene encoding methylenetetrahydrofolate reductase in coastal West Africa.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast of Brazil.Semantic proximity Read ↗

Transcobalamin 776C->G polymorphism negatively affects vitamin B-12 metabolism.Semantic proximity Read ↗

Environmental influence on the worldwide prevalence of a 776C->G variant in the transcobalamin gene (TCN2).Semantic proximity Read ↗

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