Article
High prevalence of hyperhomocysteinemia related to folate deficiency and the 677C-->T mutation of the gene encoding methylenetetrahydrofolate reductase in coastal West Africa.
The American journal of clinical nutrition - 1 Apr 2004
Amouzou Emile K, Chabi Nicodème W, Adjalla Charles E, Rodriguez-Guéant Rosa M, Feillet François, Villaume Christian, Sanni Ambaliou, Guéant Jean-Louis
Abstract excerpt
BACKGROUND: Moderate hyperhomocysteinemia is a risk for neural tube defect and neurodegenerative and vascular diseases and has nutritional, metabolic, and genetic determinants. Its prevalence in sub-Saharan Africa remains unknown. OBJECTIVE: Our goal was to evaluate the prevalence of hyperhomocysteinemia and the influence of nutritional, metabolic, and genetic determinants in savanna and coastal regions of Togo...
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