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Association between Methylene-Tetrahydrofolate Reductase C677T Polymorphism and Human Immunodeficiency Virus Type 1 Infection in Morocco.

Laboratory medicine - 5 Jan 2023

Baba Hanâ, Bouqdayr Meryem, Saih Asmae, Bensghir Rajaa, Ouladlahsen Ahd, Sodqi Mustapha, Marih Latifa, Zaidane Imane, Kettani Anass, Abidi Omar, Wakrim Lahcen

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) infection varies substantially among individuals. One of the factors influencing viral infection is genetic variability. Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is a genetic factor that has been correlated with different types of pathologies, including HIV-1. The MTHFR gene encodes the MTHFR enzyme, an essential factor in the folate metabolic...

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PMID: 36036632
DOI: 10.1093/labmed/lmac081

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