Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis

22 Jan 2008

Abstract excerpt

We have investigated how Wnt and vitamin D receptor signals regulate epidermal differentiation. Many epidermal genes induced by beta-catenin, including the stem cell marker keratin 15, contain vitamin D response elements (VDREs) and several are induced independently of TCF/Lef. The VDR is required for beta-catenin induced hair follicle formation in adult epidermis, and the vitamin D analog EB1089 synergizes with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer and Skin Lesions
Share to Hair Growth and Disorders
Share to Hedgehog Signaling Pathway Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18213391
DOI: 10.1371/journal.pone.0001483

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult EpidermisPMID 18213391Read ↗

MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway.Semantic proximity Read ↗

Vitamin D receptor is essential for normal keratinocyte stem cell functionSemantic proximity Read ↗

Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development.Semantic proximity Read ↗

From basal cell carcinoma morphogenesis to the alopecia induced by hedgehog inhibitors: connecting the dotsSemantic proximity Read ↗

Repigmentation of Human Vitiligo Skin by NBUVB Is Controlled by Transcription of GLI1 and Activation of the β-Catenin Pathway in the Hair Follicle Bulge Stem CellsSemantic proximity Read ↗

1α,25-Dihydroxyvitamin D3 Modulates the Hair-Inductive Capacity of Dermal Papilla Cells: Therapeutic Potential for Hair RegenerationSemantic proximity Read ↗

Dlx3 is a crucial regulator of hair follicle differentiation and cyclingSemantic proximity Read ↗

Identification of transcriptional targets of Wnt/β-catenin signaling in dermal papilla cells of human scalp hair follicles: EP2 is a novel transcriptional target of Wnt3aSemantic proximity Read ↗

WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation.Semantic proximity Read ↗

Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar.Semantic proximity Read ↗

The cell cycle regulator protein 14-3-3σ is essential for hair follicle integrity and epidermal homeostasis.Semantic proximity Read ↗

Clinicopathologic and molecular characterization of a series of sporadic trichoblastic neoplasms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.