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Article

In vitro susceptibility of various genotypic strains of Toxoplasma gondii to pyrimethamine, sulfadiazine, and atovaquone.

Antimicrobial agents and chemotherapy - 1 Apr 2008

Meneceur Pascale, Bouldouyre Marie-Anne, Aubert Dominique, Villena Isabelle, Menotti Jean, Sauvage Virginie, Garin Jean-François, Derouin Francis

Abstract excerpt

Sulfadiazine, pyrimethamine, and atovaquone are widely used for the treatment of severe toxoplasmosis. Their in vitro activities have been almost exclusively demonstrated on laboratory strains belonging to genotype I. We determined the in vitro activities of these drugs against 17 strains of Toxoplasma gondii belonging to various genotypes and examined the correlations among 50% inhibitory concentrations (IC50s),...

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Identifiers

PMID: 18212105
DOI: 10.1128/AAC.01203-07
PMCID: PMC2292506

Genes

DHFR
DHPS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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